Medical description: Ampicillin is a drug that belongs to the group of antibiotics. Although this is not quite a new drug, it is still widely used in medical practice. This is semi synthetic penicillin that is produced in dry form for dilution with water and internal usage in form of capsules and as a lyophilizate for dilution with water for injections. Once the drug gets into the body, it affects the state of cell membranes, thus killing many types of pathogens. If you suffer from a disease that is provoked by germs that are sensitive to the drug, the given medication can help you.
Synonyms: Ampicilin, Apmax
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care professional before using any drug.
What is Ampicillin and why is it effective?
Ampicillin is an antimicrobial agent, also known as semi synthetic penicillin, which is often used by the treatment of diseases that are caused by mixed infection. The medication is also received in order to treat a variety of other infections of bacterial origin - bronchitis, pneumonia, certain lung infections, ear, urinary tract, skin and other different diseases.
Generic Ampicillin is taken for the treatment of post-operative soft tissue infections, pyodermas, infections of the digestive system that are caused by microorganisms sensitive to it (cholecystitis, intestinal infections, enterocolits caused by Salmonella, enteric and dysentery bacillus), tonsillitis, laryngitis, pleurisy, peritonitis, sepsis and many others ailments.
In connection with the fact that the release of the medication with urine is in an unmodified form and in high concentrations, the drug is very effective for infections of the genitourinary system (pyelitis, cystitis, gonorrhea) that are caused by Escherichia coli, Proteus, enterococci, or mixed infection. The given substance is prescribed for respiratory infections (pneumonia, bronchopneumonia, lung abscesses, bronchitis and chronic bronchitis, which are caused by a stick Pfeiffer - Haemophylus influenzae) that are poorly treatable with the help of other antibiotics. You can order Generic Ampicillin at one of the reliable online pharmacies.
Pharmacological action and dosage of the drug.
If you want to buy Generic Ampicillin, you should know that it is one of the antibiotics belonging to the group of semi synthetic broad-spectrum penicillins. Its bactericidal effect is manifested by inhibiting bacterial cell wall synthesis. The drug is very effective to use against gram-positive aerobic bacteria, gram-negative aerobic bacteria and some strains of Haemophilus influenzae.
The medication is produced in tablets, capsules, in form of powder for preparation of solution, in granules for suspension and as a lyophilisate for the preparation of solutions for intramuscular and intravenous reception. The dosage of the drug is prescribed strictly individually, depending on the nature and severity of the disease the patient suffers from, susceptibility and localization of the infection. Single dosage of the tablets for adult patients is from 250 to 500 mg at a daily dose of 1 to 3 grams. For children weighing less than 20 kg the daily dosage is 12.5-25 mg per kg. For those who weigh more than 20 kg it is from 50 to 100 mg per kg.
Daily dosage is usually divided into 4 receptions. On the duration of the treatment affect the nature and severity of infection and the effectiveness of treatment. Ampicillin tablets can be received without food. In order to prepare a suspension, you should add to the vial with the antibiotic 62 ml of distilled water. The finished suspension is washed down with water. For parenteral injection the single dosage of the drug for the adult patients consists of 250-500 mg for a daily dosage of 1-3; with the particularly severe infections daily dose can be increased to 10 grams or more.
For newborn babies Ampicillin is prescribed in a daily dosage of 100 mg per kg of body weight, for older children it is 50 mg per kg. By more severe infections, the dosage is usually doubled. The daily dosage is divided into 4-6 receptions with the intervals in 4-6 hours. Duration of intramuscular reception is usually up to 7-14 days, and the duration of intravenous reception of Ampicillin is 5-7 days with a further transition to the intramuscular route of reception.
Solution for intramuscular reception is prepared by diluting the contents of the vial with 2 ml of water for injection. According to the instruction for the usage of the drug, intravenous bolus dose (up to 2 grams) is to be dissolved in 5-10 ml of water for injection and slowly administered over 5 minutes. If a single dosage is greater than 2 grams, the drug is administered intravenously.
Ampicillin is usually well tolerated, but sometimes there may be dyspepsia (belching, nausea, vomiting). There can be a phenomenon of dysbiosis associated with the effect of the drug on the intestinal flora (increased flatulence, diarrhea, candidiasis), and allergic reactions (hives, spotty-nodular rash) by patients with enhanced individual sensitivity to penicillin.
You cannot use the drug is you have individual hypersensitivity to penicillin, severe renal impairment, allergic diseases (hay fever, asthma). With great care Ampicillin is prescribed to patients with impaired hepatic function. Drinking of alcohol during treatment with the help of this drug is absolutely contraindicated.
Interaction with other drugs.
Glucosamine, aminoglycosides, antacids and laxatives delay the absorption of the drug and ascorbic acid, on the contrary, increases it. Bacteriostatic agents have antagonistic action on Ampicillin, and bactericidal antibiotics have a synergistic effect. The medication enhances the effectiveness of anticoagulants, but it reduces the effectiveness of oral contraceptives.
Phenylbutazone, oxyphenbutazone, allopurinol, diuretics, nonsteroidal antiinflammatory drugs, and drugs that stop the tubular secretion, increase the concentration of Ampicillin. Allopurinol when combined with Ampicillin pills increases the risk of skin rash. The drug blunts clearance, increases the toxicity of methotrexate and activates the absorption of digoxin.
Ampicillin is an effective antibiotic which is quite often used for the treatment of such diseases as pneumonia, urinary tract and bronchitis.
Ampicillin – an effective drug in modern pharmaceutics.
Ampicillin is an efficient drug that belongs to the group of antibiotics. Although it is not a new drug, it is still widely used in medical practice. It is semi-synthetic penicillin that is produced in dry form for dilution with water and internal usage, as well as capsules and as a lyophilizate for dilution with water for injections. Once ingested, the medication affects the state of cell membranes, thus killing many types of pathogens.
Ampicillin is a white crystalline powder that has a bitter taste which is stable in an acidic environment. This substance is prepared by acylation of 6-aminopenicillanic acid with the residue of aminophenylacetic acid. The medication is not destroyed in the acidic environment of the stomach; instead it is quite well absorbed when it is taken orally. The given medication is active against gram-positive microorganisms. The drug also enhances the action of oral anticoagulants.
In what cases the drug is prescribed?
If you want to buy Generic Ampicillin, you should be aware of the situations when it is useful to take it. For example, the drug is quite helpful when you suffer from a disease that is provoked by microbes susceptible to it, such as inflammation of the upper respiratory tract, respiratory system, urogenital system, Chlamydia and gonorrhea. Also the medication is appointed to those patients who have festering wounds, infected burns, infectious lesions of movement and the digestive tract, meningitis or blood poisoning.
Ampicillin is not prescribed if you are hypersensitive to preparations of penicillin group, carbapenems and cephalosporins. You also cannot use this drug for the treatment if you have severe liver disease, lymphocytic leukemia, mononucleosis and severe diseases of the digestive system. You should not receive the drug during breastfeeding and for the treatment of children of the first month of life. If you suffer from allergic diseases, you should be cautious when using this medicine as your treatment. Do not use the drug without prescription while pregnancy period or in case of kidney disease.
What about reviews?
The given medication has got a lot of positive reviews from different people around the world. Practically all of them were pleased with the drug action and with the results they got. Here are a few reviews about the drug usage.
Natalie, a nurse, 24 years old: «It happened to me that at the end of pregnancy I got very sick. I could not handle it without using antibiotics. The doctor offered me to have some injections of Ampicillin and I had to ask my neighbor to help me because my husband refused to do it. The first three days I was getting injections four times a day, then I had to replace ampoules with tablets since my neighbor went on vacation. Tablets appeared to be not that bad.
As far as I know, this drug refers to a group of penicillin antibiotics and has a wide spectrum of action, so it is one of the strongest medications. And this is the first antibiotic (may be one of the first) which was used in medicine. Hence its researchers studied it from different sides. I have read about side effects but I have not had any of them. There were no nausea, vomiting and stomach pains. Although I was very worried about it. But along with antibiotics there should always be taken some bacteria in order to avoid gastrointestinal disorders. So I am pretty satisfied with the given medication».