Medical description: Generic Cefadroxil is light pink powder which after adding some water forms a pink suspension with odour and taste of flavor. It is an antimicrobial substance for the systemic usage. The antibiotic is utilized for the treatment of infections evoked by sensitive to Cefadroxil microorganisms: chronic otitis media and sinusitis, pharyngitis, tonsillitis, infections of the lower respiratory tract (pneumonia, chronic and acute bronchitis), urinary tract infections (complicated and neoslojnenny), skin contagions and soft tissue infections, contagions of bones and joints.
Synonyms: S-drox, Vistadrox, Baxan, Bidocef, Cefa-Drops, Cefamox, Ceforal, Cefradroxil, Cephos, Duracef, Kefroxil, Oracefal, Sedral, Sumacef, Ultracef
Consult your helth
care professional before using any drug.
Cefadroxil is an effective drug
Generic Cefadroxil is a semisynthetic cephalosporin antibiotic that has a bactericidal effect. The arrangement of action connected with the infringement of the synthesis of components of cell membrane of bacteria. Beta-hemolytic streptococci, pneumococci and staphylococci (coagulase-positive and coagulase-negative, and breast infections with penicillinase-producing strains) are sensitive to the antibiotic of this type. After taking, the drug is almost completely absorbed in the upper segment of the small intestine. The maximum concentration in plasma is 1 to 2 hours.
The simultaneous intake with food has almost no effect on absorption. Cefadroxil is excreted much more slowly compared with other oral cephalosporins, so the interval between doses may be 12 – 24 hours. 15 – 20% of this antibiotic is connected with plasma proteins. Clinically relevant concentrations are determined in many tissues, especially in the tonsils, the tissues and fluids of the respiratory tract, in the fluids of the middle ear, eyes, muscle tissue, and also in the skin, bones and joints, liver and bile, urine, prostate and female genital organs.
The concentration of the drug in fetal blood and amniotic fluid is approximately one third of drug concentration in the serum of the mother. The given antibiotic can be retrieved in mother's milk in small amounts. Approximately 90% of the antibiotic is excreted unchanged in urine. Elimination is delayed in examinees with impaired renal function. Usually people buy Generic Cefadroxil when it is prescribed by their medical specialist for the treatment of various contagious diseases. It isn’t recommended to accept the antibiotic without doctor’s consultation.
Mode of administration and doses
Even if you order Generic Cefadroxil on the Internet, you will have a medical instruction where you will be able to find how to prepare the suspension. For preparation of the suspension, pour cooled boiled water in the bottle and shake it. Add more water to the marking, if it is needed. Before usage, shake thoroughly to ensure homogeneity of the suspension. The prepared suspension can be consumed within 4 days. This suspension is taken orally with sufficient amount of water, regardless of meal.
The average dose for children with normal renal function is 25 – 50 mg/kg of body weight per day for 1 or 2 doses with a 12 hour interval. If it is necessary, the daily dose may be increased to 100 mg/kg of body weight. Children aged 9 – 12 years (weighing 30 – 40 kg) for 1 g at day 1 or 2 reception. In severe infections the dose may be increased twice. Grown-ups and teenagers, weighing more than 40 kg with normal renal function, are appointed from 1 to 2 g daily for 1 – 2 divided doses; in severe infections the dose may be doubled. The continuance of treatment is 7 – 10 days.
The therapy should proceed for 2 to 3 days after disappearance of acute clinical symptoms. In contagions provoked by Streptococcus pyogenes, the treatment should continue not less than 10 days (children accept 30 mg/kg per day for 1 – 2 doses, adults 1G/day for 1 – 2 doses). In complicated urinary tract infections adults are appointed 1 g twice a day for 7 to 10 days. In infections of the musculoskeletal system children are appointed 50 mg/kg of body weight per day in 2 – 4 doses at 6 – to 12-hour intervals, adults 1 g at 4 doses per day with 6-hour intervals for 3 to 5 weeks (depending on the clinical picture).
In chronic renal failure (based on creatinine clearance) to avoid the cumulation of Generic Cefadroxil, the intervals’ duration between doses of the drug should be increased. In creatinine clearance 40 – 80 mg/min. of 12 hours between meals, 20 – 40 ml/min – 24 hours. <20 ml/min 48 hours. Patients, who are on hemodialysis, get half the daily dose that is appointed for 48 hours before dialysis, and the other half after dialysis. The next half of the daily dose during dialysis 2 to 3 times a week is appointed for 48 hours before subsequent dialysis procedure.
Side effects, contradictions and overdose
If you buy Generic Cefadroxil, you should be aware of possible side effects. Most often side effects can be observed from the direction of gastro-intestinal tract (nausea, vomiting, diarrhea and abdominal pain), occasionally allergic skin rash, itching, very rarely glossitis, dizziness, insomnia, anaphylactic shock. In some cases, there is a growth of opportunistic microorganisms that can cause vaginal mycosis, thrush, etc.
Contradictions are: hypersensitivity to cephalosporins. When hypersensitivity to penicillins is the potential for cross-allergy. In the treatment of wet-nurses, mild shouldn’t be used. Breastfeeding is possible after 2 days after treatment. Symptoms of overdose are: nausea, hallucinations, hyperreflexia, extrapyramidal disorders, blurred consciousness, coma, impaired kidney function.
The first aid in taking toxic dose: gastric lavage, if necessary, hemodialysis. Sometimes patients should monitor correction of fluid and electrolyte status, monitor renal function. The powder for suspension preparation is kept at the temperature of +25 °C, in dry place, protected from light and out of reach of children. The serviceable life of powder for suspension is 3 years.
Cefadroxil is a bactericidal antibiotic of the cephalosporin type, productive in Gram-positive and Gram-negative microbial contagions.
How Cefadroxil removes infectious diseases.
Generic Cefadroxil is a cephalosporin bactericidal antibiotic of a new generation that is the para-hydroxy derivation of cefalexin and is consumed equally in the treatment of easy to moderate sensitive contagions which provoke the disease popularly named strep throat or tonsillitis, infection of urinary tract , infection of reproductive tract and skin infections. This antibiotic has a wide range of activity and has been productive in curing bacteria responsible for evoking tonsillitis and contagions of skin and urinary tract.
The way the drug acts inside.
People, who usually buy Generic Cefadroxil, know that it is almost completely adsorbed from the gastrointestinal tract. After dosages of 500 mg and 1 g by mouth, peak concentration of plasma is about 16 and 30 micrograms/ml are received after 1.5 to 2.0 hours. Although high concentrations are analogous to those of cefalexin, concentrations of plasma are more preserved. Dosage with food has no influence the Cefadroxil absorption.
About 20% of the drug is noted to be bound to proteins of plasma. Its plasma period of decay is about 1.5 hours and is extended in examinees with renal disorder. Generic Cefadroxil is broadly distributed to tissues of the body and fluids. It passes the placenta and emerges in breast milk. More than 90% of a Cefadroxil dosage is removed unchanged in urine during 24 hours by glomerular filtering and tubular secretion; peak of urinary concentration of 1.8 mg/ml was noticed after a dose of 500 mg. The antibiotic is removed by hemodialysis.
Some useful information about the antibiotic.
The most commonplace side effects of are diarrhea, vomiting and upset stomach. Other side effects involve itching, hives and rashes. People order Generic Cefadroxil to use it as an antibiotic prophylaxis before dentistry procedures, for examinees allergic to penicillins. It can be utilized for curing infected injuries on the representatives of fauna. The powder combined with water has a colour and smell alike tang.
When animals are given orally, the amount is dependent on their weight and seriousness of infection. It is possible cross-allergy to penicillins (5 – 10% of cases). In patients with existing renal insufficiency intervals between meals and taking of Cefadroxil should be increased. If a patient uses the antibiotic for a long time, he/she should control blood and functional state of the liver and kidneys. If a customer has allergic reactions and diarrhea, the treatment should be discontinued. When there is suspicion of pseudomembranous colitis, caused by the methods of antibiotics, you should start treatment with vancomycin. Antiperistaltic means is contraindicated.
The prolonged treatment can cause hypovitaminosis K (hemorrhage), the ratio V (stomatitis, glossitis, neuritis, anorexia, etc.) and false positive direct Coombs test: it is necessary to mean that the positive results of Coombs test associated with the usage of Generic Cefadroxil. This also applies to newborns whose mothers were treated with cephalosporins before childbirth. Cefadroxil can reduce the effectiveness of oral contraceptives.