Medical description: Sumycin is an antibiotic from a family of tetracyclines used to treat wide range of infectious diseases starting from airways infections resulting from untreated flu and acne to cholera and syphilis. The medicine is recommended to be taken four times a day in the dosage of 0.25 -0.5 grams per intake. Maximum daily dosage of Sumycin should not exceed 4 grams. Used by kids, the dosage is calculated based on overall body weight. The length of the treatment course depends on the infection and severity of the process and should be established by a doctor.
The medicine is contraindicated during pregnancy, in breastfeeding period and to people allergic to its main active substance.
Synonyms: Alcyclin, Tetracyclin, Abramycin, Abricycline, Achromycin, Actisite, Amycin, Biocycline, Bristaciclin, Cefracycline, Ciclibion, Copharlan, Cytome, Democracin, Dumocyclin, Enterocycline, Hostacyclin, Lexacycline, Liquamycin, Micycline, Oletetrin, Omegamycin, Orlycycline, Polyotic, Resteclin, Retet, Robitet, Roviciclina, Solvocin, Tetrabon, Tetrachel, Tetrafil, Tetramed, Tetrex, Tsiklomitsin, Veracin
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Sumycin is one of the brand names under which Tetracycline is marketed. It is included in World Health Organization Model List of Essential Medicines. The antibiotic family tetracyclines to which the medicine belongs was discovered in 1945 by Lederle Laboratories, an American pharmaceutical company. Tetracyclines then were not synthesized but found as natural products. The medicine was first used in 1948. Later, in 1950, the chemical formula for the creation and alteration of the medicine was found by Harvard University professor Robert Burns Woodward, who patented his method of fermentation and production of the substance.
Sumycin is a wide range antibiotic effective both against Gram-negative and Gram-positive bacteria. It is used to treat diseases caused by aerobic and anaerobic bacteria. Currently, there are known only two types of bacteria resistant to Sumycin - Pseudomonas aeruginosa and Proteus. The medicine can also become ineffective in previously effectively treated bacteria elimination due to acquired resistance. Inappropriate use or exceeding of the prescribed treatment course length may result in resistance developed in the treatment of neisseria gonorrhoeae, staphylococcus, streptococcus, and anaerobic bacteria.
Sumycin mechanism of action
Sumycin prevents complex formation between transfer RNA and ribosome leading to a suppression of protein synthesis in bacteria. It inhibits the plantation of new amino acids to the arising peptide chain. Sumycin and other tetracyclines are much less harmful for the body cells than to bacterial cells due to the fact that bacteria actively absorbs Sumycin into their cytoplasm while human or other mammals body cells do not do so.
Chemical properties of Sumycin
The formula of the medicine used for oral intake is C22H24N2O8.
Oral Suspension of Sumycin, beside the active substance, consists of inactive additives: purified water, sucrose, citric acid, flavor, colorant, potassium citrate, potassium metaphosphate, saccharin sodium, sodium metabisulfite, sodium benzoate, sodium citrate, sorbitol solution, and tragacanth.
Pharmacokinetics of Sumycin
The medicine is not fully absorbed from the gastrointestinal tract when taken orally. The maximum concentration of the medicine in plasma is achieved after from two to four hours after the oral intake. Sumycin is mostly concentrated in bile, but excreted with urine and feces. The quality of urinal excretion highly depends on the kidney function as the excretion with urine requires proper glomerular filtration.
When Sumycin is prescribed
Sumycin or identical medicines with other registered names are prescribed for wide range of infections treatment caused by susceptible pathogens: pneumonia and respiratory tract infections caused by Mycoplasma pneumonia, respiratory tract infections caused by Haemophilus influenzae and Klebsiella spp., bacterial infections of the urogenital system, skin and soft tissues infections, including anaerobic, necrotizing gingivostomatitis, conjunctivitis, rosacea, actinomycosis, intestinal amebiasis, anthrax, brucellosis, bartonellosis, chancroid, cholera, uncomplicated gonorrhea, inguinal granuloma, lymphogranuloma venereum, listeriosis, plague, psittacosis, rickettsial pox, Rocky Mountain spotted fever, typhus, relapsing fever, syphilis, trachoma, tularemia, yaws, and others. Currently the medicine is also prescribed to treat acne.
The release form of Sumycin
Depending on the manufacturer, the medicine is supplied in form of oral tablets, oral capsules, oral suspensions, and compounding powder of different dosage of active substance.
Dosages of Sumycin
For adults, the medicine is prescribed to be taken 250-500 milligrams 4 times a day or 500-1000 milligrams every 12 hours. The maximum daily dosage is 4000 milligrams or 4 grams.
In the treatment of acne, the dosage of Sumycin is from 0.1 to 0.15 grams a day divided in two intakes. In case of acne improvement (usually it occurs in 3 weeks of use) the dosage is gradually decreased to the supporting one of 0.125-1 grams a day. The best results are observed using the medicine every other day or by intermittent therapy.
The treatment of brucellosis requires the intake of 0.1-0.15 grams of Sumycin every 6 hours during 3 weeks along with the use of 1 gram of streptomycin every 12 hours during one week one time a day, and once a day during the following two weeks of treatment.
In the treatment of uncomplicated gonorrhea, the initial single dose is 1.5 grams with following 0.3 grams every 6 hours during 4-day-course (the total dose should be 9 grams for a course).
Syphilis is treated with Sumycin as follows: 0.2 grams every 6 hours during 15 days (early syphilis) and 30 days in the treatment of tertiary (late) syphilis.
Uncomplicated urethral, endocervical, and rectal infections caused by Chlamydia trachomatis are treated using 0.3 grams of the medicine 4 times a day during no less than 7 days. In the treatment of these diseases in children over 8 years old, the dosage is 6.25-12.5 microgram per kilogram of body weight every 6 hours or 12.5-25 microgram per kilogram of body weight every 12 hours.
Contraindications and combination with other medicines
Sumycin is contraindicated to pregnant women during second and third trimesters of pregnancy, to breastfeeding women, children under age of 8, and patients with leucopenia. It should be carefully used by patients with renal failure and stomach ulcer.
The medicine is commonly prescribed to be taken along with antifungal medicines and the medicines to normalize intestinal flora which is damaged during the use of the antibiotic.
Adverse reactions of Sumycin
The medicine can cause the following side effects: increased sensitivity of skin to sunlight, nausea and vomiting, diarrhea, headache, loss of appetite, abdominal pain, burning of the stomach, itching, rectal or genital itching, skin rash, and others.
Buy Sumycin online to save money and get the most effective treatment of your infection. Read the general information and useful tips in the article.
One of the most widely used antibiotics in the world is Tetracycline. Currently, there are hundreds of the identical medicines to Tetracycline marketed under different brand names, for example, Generic Sumycin. The popularity of the medicine among doctors is based on its high effectiveness in the treatment of wide spectrum of bacteria, including Gram-positive and Gram-negative bacteria and even anaerobes which are quite hardly eliminated. The medicine was first discovered in 1945 and used in 1948. It was based on the non-synthesized, natural Tetracyclines. Nowadays, after multiple tests and trials, the medicine have become even more effective as it can be altered to fight the most recently found types of bacteria and prevent resistance to the drug.
When Generic Sumycin is prescribed?
The medicine is prescribed for a wide range of infections and diseases. Most known to wide public are: certain types of pneumonia, syphilis, various respiratory tract infections, bacterial infections of the genitourinary system, conjunctivitis, acne, and other soft tissue infections.
Before starting the treatment with Generic Sumycin, it is preferable to find out the infectious agent (the type of bacteria that caused the disease) in order to be sure that it is sensitive to the active substance of the medicine.
How Generic Sumycin is used?
Whether you opt to buy Generic Sumycin online without prescription or at your local pharmacy, you must follow your doctor instructions. The medicine is used in different dosage for various diseases. The common dosage for the most wide spread diseases is 0.25-0.5 grams 4 times a day or 0.500-1gram every 12 hours. The maximum daily dosage is 4 grams. However, the treatment course and administration techniques can vastly vary, so be sure to receive a comprehensive medical consultation before starting the course of Generic Sumycin.
When Generic Sumycin is contraindicated?
Primarily, the medicine is contraindicated to people who are allergic to the components of the medicine, pregnant women during II and III trimesters of pregnancy and after giving birth while they breastfeed. Children aged less than eight years are also prohibited to take the medicine.
It is also advised to take the medicine cautiously, possibly reducing the dosage, in kidney failure and stomach ulcer. The medicine is almost completely excreted in feces and urine, therefore it is crucial to have healthy kidneys to filter the medicine and flash it out of the body after its work is done.
What possible side effects the medicine can cause?
In general, Generic Sumycin is considered relatively safe. It rarely provokes severe side effects in people who are not allergic to its ingredients. However, the intake may cause nausea, vomiting, and other indigestive problems, diarrhea, headache, dizziness, genital and rectal itching, skin rash and so on. It is advised to consult your health care provider immediately in occurrence of even the slightest symptoms of side effects in order to prevent serious harm to your health.
Where to buy Generic Sumycin cheaper?
You can buy Sumycin at your local drugstore if you have sufficient funds for the whole treatment course or look for the medicine online. Buying the drug from an online pharmacy you can opt either for Sumycin or its cheaper analogs manufactured in India, Argentina, Russia and other countries. If you buy cheaper Sumycin analog, be ready to see a different name on a package. Each company manufacturing the drug registers its own trademark. The dosages per pill or capsule may also deviate, so make sure to check them before you finalize the order.